Niacin cures systemic NAD+ deficiency and improves muscle performance in adult-onset mitochondrial myopathy
Pirinen E, Auranen M, Khan NA, et al.
Key finding
Niacin restored NAD+ and improved muscle function in mitochondrial myopathy patients.
Summary
10-month niacin titration in patients with mitochondrial myopathy restored muscle NAD+ and improved strength and muscle mass — the clearest clinical efficacy result for any NAD+ precursor.