Delivery Methods
How a precursor enters the body matters more than most users think. Bioavailability, cost, and the right match for each molecule vary considerably across routes.
Oral Capsule
The default route — enteric or standard gel capsule
Bioavailability: moderate·Cost: low
Sublingual
Buccal absorption bypasses gut and hepatic first-pass
Bioavailability: high·Cost: moderate
Liposomal
Phospholipid encapsulation for enhanced tissue uptake
Bioavailability: high·Cost: premium
IV Drip
Direct infusion of NAD+ itself — clinic-only
Bioavailability: high·Cost: premium
Subcutaneous Injection
At-home clinical NAD+ administration
Bioavailability: moderate·Cost: high
Intranasal
Emerging route for direct CNS delivery
Bioavailability: variable·Cost: high
Oral Powder
Bulk powder for precise dose customization
Bioavailability: moderate·Cost: low
Topical
Niacinamide for barrier repair and photoprotection
Bioavailability: variable·Cost: moderate