Safety and metabolism of long-term administration of NIAGEN (Nicotinamide Riboside Chloride) in healthy middle-aged and older adults
Conze D, Brenner C, Kruger CL
Key finding
NR is well tolerated at doses up to 1 g/day over 8 weeks in healthy adults.
Summary
8-week, randomized controlled trial of NR at 100, 300, 1,000 mg/day vs. placebo. No clinically meaningful safety signals across the dose range.
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