Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
Trammell SAJ, Schmidt MS, Weidemann BJ, et al.
Key finding
NR is orally bioavailable in humans and raises blood NAD+ without flushing.
Summary
First human pharmacokinetic data for NR. Single oral doses of 100-1,000 mg raised blood NAD+ in a dose-dependent fashion without flushing or adverse events.
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