Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Martens CR, Denman BA, Mazzo MR, et al.
Key finding
NR at 1 g/day raises NAD+ ~60% and may reduce systolic BP in adults with Stage 1 hypertension.
Summary
6-week crossover trial of 1 g/day NR in middle-aged and older adults. Raised NAD+ ~60% and reduced systolic blood pressure in a subgroup with elevated baseline BP.
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